Microcirculatory Dysfunction in Inflammatory Injury
by Sarah Yuan, M.D., Ph.D
April 16, 2021 at 3:00 pm ET

Sarah Yuan, M.D., Ph.D., is Professor and Chair of the Department of Molecular Pharmacology and Physiology at University of South Florida Morsani College of Medicine, where she also serves as Professor of Surgery and holds the Deriso Endowed Chair in Cardiovascular Disease. With a training background as a trauma surgeon, Dr. Yuan has been conducting translational research aimed at discovering novel molecular mechanisms underlying system/organ pathophysiology with diagnostic and therapeutic implications. Her work focuses on the cellular and molecular control of microcirculatory function in inflammation. Currently, her laboratory investigates blood and endothelial cell-cell interactions that regulate vascular barrier integrity following trauma and sepsis. Her group is known for their expertise in studying endothelial permeability and developing innovative approaches for integrated analysis of human, animal, and cell models of inflammatory injury. Since 1994, her research has continuously been funded by the NIH, which has not only resulted in many high-impact publications, but also provided numerous training opportunities for physicians and basic scientists across multiple disciplines. The majority of her mentees have successfully advanced in their academic or research careers. Her achievements have been recognized nationwide with a number of prestigious honors and awards, including the Landis Award from the Microcirculatory Society, Fellow of the American Physiology Society, Fellow of American Association for the Advancement of Science, an elected member of Alpha Omega Alpha Honor Medical Society. Most recently, she received the NHLBI Outstanding Investigator Award.