Moderators
Sean Monaghan MD, Brown University
John Lyons MD, Emory University

Plenary Session I – Immunologic Perspectives in Sepsis

Invited Speakers

• 1:05 PM – 1:25 PM: Julia Bohannon Ph.D., Vanderbilt University, Trained Immunity as a Strategy for Preventing Infection and Sepsis after Burn Injury
• 1:25 PM – 1:45 PM: Sean Monaghan MD, Brown University, RNA Biology in Sepsis
• 1:45 PM – 2:05 PM: John Lyons MD, Emory University, Cell Death Proteins as Mediators of the Host Response in Sepsis
• 2:05 PM – 2:25 PM: Vidula Vachharajani MD, Cleveland Clinic, Immune Response Transition During Sepsis Progression
• 2:25 PM – 2:45 PM: Scott Brakenridge MD, University of Washington, Biomarkers, Phenotypes & Endotypes in Sepsis: Concepts, Definitions & Future Directions

Moderators
Scott Brakenridge MD, University of Washington

Lucy Kornblith MD, University of California San Francisco  

Plenary Session II – Best of the Best: Top-Rated Abstracts

Oral Abstracts

• 2:45 PM – 3:00 PM: Zhangying Chen, Northwestern University, ANTI-CD49D ANTIBODY TREATMENT REJUVENATED EXHAUSTED CD8+ T CELLS IN AGED MICE AFTER TRAUMATIC BRAIN INJURY (Abstract 4082825)
• 3:00 PM – 3:15 PM: Stephanie Patterson, Monroe Carell Junior Children's Hospital at Vanderbilt, DELAYED GASTROINTESTINAL MICROBIAL DIVERSIFICATION IN HOSPITALIZED INFANTS WITH CONGENITAL HEART DISEASE (Abstract 4076530)
• 3:15 PM – 3:30 PM: Alexandria Byskosh, Brigham and Women’s Hospital UNTAMED IMMUNITY: USING "DIRTY" MICE AS A NEW PARADIGM FOR TRANSLATABLE TRAUMA IMMUNOLOGY RESEARCH (Abstract 4079297)
• 3:30 PM – 3:45 PM: Kenneth Meza Monga, University of Colorado, A NOVEL APPROACH TO BURN-INDUCED CARDIAC DAMAGE: THE ROLE OF HEPATIC FGF21 IN AGED MICE (Abstract 4080500)
• 3:45 PM – 4:00 PM: Matt Stier, Vanderbilt University Medical Center

  METABOLIC REWIRING OF THE CD4 T CELL COMPARTMENT IN HUMAN CRITICAL ILLNESS AND SEVERE SEPSIS (Abstract 4080810)

Moderators
Dan Remick MD, Boston University School of Medicine
Julia Bohannon Ph.D., Vanderbilt University Medical

Plenary Session III – Shock Journal: State of the Journal & Oral Presentations of Most Downloaded Papers

Invited Speakers

• 4:15 PM – 4:35 PM: Dan Remick MD,  Boston University School of Medicine State of the Journal
• 4:35 PM – 4:45 PM: Ahmed Shible, PharmD, University of North Carolina Health, Evaluation of hydrocortisone, vitamin C, and thiamine for the treatment of septic shock: A randomized controlled trial (THE HYVITS TRIAL)
• 4:45 PM – 4:55 PM: Chase Salmon, Indiana University, Evaluation of tranexamic acid and calcium chloride in major traumas in a prehospital setting: A narrative review
• 4:55 PM – 5:05 PM: Trine Lynghaug, The Artic University of Norway, How should tranexamic acid be administered in hemorrhagic shock? Continuous serum concentrations in a swine model. 
• 5:05 PM – 5:15 PM: Marc Maegele, MD Cologne-Merheim Medical Center, New insights into the pathophysiology of trauma and hemorrhage

Moderators
Tyler Loftus MD, University of Florida-Gainesville

Plenary Session IV – Advancements in Precision Medicine in Trauma and Sepsis

Invited Speakers

• 9:00 AM – 9:20 AM: Jeff Choi MD MSc, Stanford University, AI and Clinical Decision Support Models: Pitfalls Overshadowing Promises
• 9:20 AM – 9:40 AM: Amelia Maiga MD, Vanderbilt University
  AI in Prognostication for Critically Injured Patients
• 9:40 AM – 10:00 AM: Gabriel Brat MD, Beth Israel Deaconess Medical Center
  Integrating Human Intuition with AI Modeling

Oral Abstracts

• 10:00 AM – 10:10 AM: Jeremy Balch, University of Florida, TRANSCRIPTOMIC EVIDENCE THAT CRITICAL ILLNESS INDUCES AN EARLY EXPANSION OF MULTIPLE MYELOID IMMUNE SUPPRESSIVE SUBSETS (Abstract 4082825)
• 10:10 AM – 10:20 AM: Zander Tyler, University of South Florida, PREDICTING UNPLANNED TRAUMA ICU ADMISSIONS USING INTERPRETABLE MACHINE LEARNING (Abstract 4076569)
• 10:20 AM – 10:30 AM: Angelos Vasilopoulos, Loyola University, CLINICAL VARIABLE-BASED PREDICTION OF ACUTE RESPIRATORY DISTRESS SYNDROME ENDOTYPES (Abstract 4072286)

Moderators
Juan Idrovo MD, University of Colorado

Young Investigators – Oral Presentations By and For Young Investigators
(Young Investigators only – bring lunch into the room)

Young Investigators

• 12:10 PM – 12:22 PM: Seibi Kobara, Emory University, ALTERED SPHINGOLIPID BIOSYNTHESIS DURING ARDS WAS ASSOCIATED WITH PHYSICAL IMPAIRMENT AT HOSPITAL DISCHARGE IN SURGICAL ICU PATIENTS (Abstract 4074945)
• 12:22 PM – 12:34 PM: Ikechukwu Jacob, SUNY Upstate Medical Center, SURVIVING DEADLY LUNG INFECTIONS: DIFFERENTIAL IMMUNOMODULATORY ROLES OF HUMAN SP-A VARIANTS IN RESPONSE TO SARS-COV-2 INFECTION (Abstract 4082887)
• 12:34 PM – 12:46 PM: Arielle Ayotte, University of Florida, PLASMA EXTRACELLULAR VESICLE MIRNA CARGO AND RESULTANT MACROPHAGE IMMUNE REPROGRAMMING ARE ASSOCIATED WITH POOR OUTCOMES AFTER SEPSIS (Abstract 4082887)
• 12:46 PM – 12:58 PM: Ozel Mehves, University of Pittsburgh Medical Center, DOGMA-SEQUENCING ANALYSIS OF AGE-DEPENDENT RESPONSE TO MAJOR ELECTIVE SURGERY REVEALED A PRO-INFLAMMATORY AND DYSREGULATED SUBSET OF CD14+ MONOCYTES IN AGED PATIENTS AFTER SURGERY (Abstract 4083731)
• 12:58 PM – 1:10 PM: Ava Mokhtari, The University of Texas Health Science Center at Houston, TREATMENT WITH HEPARAN SULFATE ANTAGONIST, SURFEN, TO BLOCK ENDOTHELIAL-ANTITHROMBIN INTERACTIONS, MITIGATES THE PULMONARY PROTECTIVE EFFECTS OF PLASMA AFTER HEMORRHAGIC SHOCK (Abstract 4082198)

Moderators
Myung Park MD, Mayo Clinic
Lauren Moffatt PhD, MedStar Health Research Institute

New Investigators – New Investigator Competition

New Investigators

• 1:20 PM – 1:35 PM: Matthew Alves, University of Florida, MULTIMODAL NUCLEAR FACTOR-ERYTHOID-2-RELATED FACTOR (NRF2) THERAPY IN THE CONTEXT OF MAMMALIAN TARGET OF RAPAMYCIN (MTOR) INHIBITION REGULATES IMMUNE REPROGRAMMING IN RESPONSE TO INFECTION EARLY AFTER BURN AND INHALATION INJURY (Abstract 4083092)
• 1:35 PM – 1:50 PM: Joseph Krocker, University of Texas Health Science Center at Houston, CIRCULATING TRPM4 AND SUR1 AND CLINICAL OUTCOME FOLLOWING TRAUMATIC BRAIN INJURY (Abstract 4083558)
• 1:50 PM – 2:05 PM: Grace Bonson, University of Vermont, ENDOTHELIAL-SPECIFIC ABLATION OF THE SCRAMBLASE TMEM16F REDUCES IN VIVO CLOT FORMATION IN MICE (Abstract 4081204)
• 2:05 PM – 2:20 PM: Meagan Kingren, University of Arkansas, HOUSING TEMPERATURE ALTERS BURN-INDUCED HYPERMETABOLISM IN MICE (Abstract 4077893)
• 2:20 PM – 2:35 PM: Russell Hollis, Northwell Health Feinstein Institutes for Medical Research, A NOVEL OPSONIC EXTRACELLULAR CIRP INHIBITOR MOP3 ALLEVIATES GUT ISCHEMIA/REPERFUSION INJURY (Abstract 4076905)

Moderators
Myung Park MD, Mayo Clinic
Lauren Moffatt PhD, MedStar Health Research Institute

Research Awards – Research Fellowship Recipient Presentations

Awardee Speakers

• 2:45 PM – 3:00 PM:  Faculty Research Award Recipient
  Patricia DeAssis University of Michigan ([email protected])
  Metabolic reprogramming of CD4 T cells: Implications for post-sepsis immunosuppression

• 3:00 PM – 3:15 PM: Research Investigator Fellowship Recipient
  Min Fan ([email protected])  POSTPONED TO 2025
  Novel role of lactate in MDSC-mediated immunosuppression in sepsis

• 3:00 PM – 3:15 PM: Japan Shock Society Presidents Award
  Tadashi Matsuoka MD PhD, Keio University ([email protected])
  Resuscitative Endovascular Balloon Occlusion of the Aorta with downstream intra-aortic irrigation using hydrogen-containing solution mitigates ischemic injury in a swine hemorrhagic shock with liver injury

• 3:15 PM – 3:30 PM: Japan Shock Society Chairmans Award
  Kensuke Nakamura ([email protected])
  Vasopressin loading for refractory septic shock (VALOR) study: A prospective observational study

Moderators
Linda Sousse PhD MBA, Institute for Extracorporeal Life Support
Jeff DellaVolpe MD MPH, Institute for Extracorporeal Life Support

Parallel Session 1 – Addressing the Pathophysiology of Severe Lung Injury: A Translational Approach with ECMO

Invited Speakers

• 4:00 PM – 4:20 PM: Linda Sousse PhD MBA, Institute for Extracorporeal Life Support, Pathophysiology of respiratory ECMO
• 4:20 PM – 4:40 PM: Lorraine Ware MD, Vanderbilt University Medical Center
  ARDS and ECMO
• 4:40 PM – 5:00 PM: Marc Maybauer MD PhD, University of Florida, Veno-Pulmonary ECMO-A new era in acute mechanical circulatory support
• 5:00 PM – 5:20 PM: Eddy Fan MD PhD, Toronto General Hospital Research Institute, Clinical presentation in V-V-ECMO

Oral Abstracts

• 5:20 PM – 5:30 PM: Raleigh Garner, National Jewish Health, COAGULATION FACTOR XIII-A AUGMENTS INFLAMMATION AND IS PRODUCED BY MONOCYTE-DERIVED MACROPHAGES DURING ACUTE LUNG INJURY (Abstract 4079376)

4:00 PM – 5:30 PM

Moderators
Charles Wade PhD, the University of Texas Health Science Center at Houston
Chris Barrett MD, University of Nebraska Medical Center

Parallel Session 2 – Hemorrhagic Shock and Clinical Applications

Invited Speakers

• 4:00 PM – 4:20 PM: Martin Schreiber MD, Oregon Health & Sciences University
  Resuscitation 2024 and the Future
• 4:20 PM – 4:40 PM: Chris Barrett MD, University of Nebraska Medical Center
  Novel approach to diagnosis of fibrinolytic perturbations in trauma and critical illness
• 4:40 PM – 5:00 PM: Jonathan Meizoso MD MSPH, University of Miami
  Bleeding and Clotting: Updates in Damage Control Resuscitation

Oral Abstracts

• 5:00 PM – 5:10 PM: Alan Weaver, US Army Institute of Surgical Research, INVESTIGATION INTO THE POTENTIAL ROLES OF COAGULOPATHY AND ENDOTHELIOPATHY ON SURVIVAL IN A SWINE MODEL OF UNCONTROLLED HEMORRHAGE (Abstract 4079016)
• 5:10 PM – 5:20 PM: Joud Mulla, University of Pittsburgh, INVESTIGATING CASPASE-11 AND GASDERMIND IN INFLAMMATORY RESPONSES AND COAGULOPATHY POST-POLYTRAUMA (Abstract 4083489)
• 5:20 PM – 5:30 PM: Boyang Ren, University of Maryland, IDENTIFYING PLASMA MICRO-RNA BIOMARKERS IN TRAUMA PATIENTS (Abstract 4076194)

Moderator
Vanessa Nomellini MD PhD, University of Texas Southwestern

Xiaoli Zhao PhD, Program Director, NIGMS

Demystifying NIH Application Session

• Elizabeth Kovacs, Ph.D., University of Colorado, Which grant is right for me, and what is the NIH review process?
•  Rosemary Kozar MD PhD, What goes into the Personal Statement?
•  Tim Billiar MD, University of Pittsburgh, Tips and tricks to writing highly fundable applications
• Judith Hellman MD, University of California San Francisco, Responding to the summary statement

Moderators
Judith Hellman MD, University of California, San Francisco

Todd Constantini MD PhD University of California San Diego

Plenary Session V – The Nervous System as a Target and Regulator of Sepsis and Critical Illness

Invited Speakers

• 9:00 AM – 9:20 AM: Cliff Deutschman MD, Feinstein Institute
  Orexinergic modulation of inflammation and organ dysfunction/injury
• 9:20 AM – 9:40 AM: Luis Ulloa PhD, Duke University
  The autonomic nervous system in sepsis and injury
• 9:40 AM – 10:00 AM: Raj Aneja MD, University of Pittsburgh
  Sepsis-associated brain injury: Understanding the role of SUR1-TRPM4

Oral Abstracts

• 10:00 AM – 10:10 AM: Quan Vo, University of Florida, SEPSIS INDUCES PERSISTENT SEX-DIMORPHIC IMMUNE ACTIVATION AND EXACERBATES AMYLOID β PATHOLOGY IN AN AD MOUSE MODEL (Abstract 4075844)
• 10:10 AM – 10:20 AM: Huan Yang, Northwell Health Feinstein Institutes for Medical Research, ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR-DEPENDENT SIGNALING REGULATES NEURONAL HMGB1 RELEASE (Abstract 4078843)
• 10:20 AM – 10:30 AM: Ayman Youssef, Duke Medicine, VAGAL STIMULATION RESOLVES COLITIS THROUGH THE DIFFERENTIAL REGULATION OF SUMO ISOFORMS (Abstract 4083707)

Moderators
Wendy Walker PhD, Mercer University
Elisabetta Liverani PhD, North Dakota State University

Plenary Session VI – DEI: Disparities and Inequities in Shock, Trauma, and Sepsis Research

Invited Speakers

• 10:45 AM – 11:05 AM: Wenjun Martini PhD, US Army Institute of Surgical Research, Promoting DEIA through the awareness of its positivity and productivity
• 11:05 AM – 11:25 AM: Elisabetta Liverani PhD, North Dakota State University, Enhancing DEIA in science and medicine through faculty hiring and retention practices
• 11:25 AM – 11:45 AM: Wendy Walker PhD, Mercer University, Supporting our diverse mentees
• 11:45 AM – 12:05 PM: Patricia De Assis PhD, University of Michigan, Enhancing DEIA in the Shock Society by increasing the visibility of individuals from underrepresented groups

Oral Abstracts

• 12:05 PM – 12:15 PM: Christina Schwenk, Technical University of Munich, School of Medicine and Health, SPICES TO COMBAT SEPSIS – CURCUMIN PIPERIN COMBINATION INCREASES THE SURVIVAL RATE IN A TWO-HIT-TRAUMA MODEL (Abstract 4078186)

Moderators
Jeff DellaVolpe MD MPH, Institute for Extracorporeal Life Support
Linda Sousse PhD MBA, Institute for Extracorporeal Life Support

Parallel Session 1 – Cardiogenic Shock: The Next Frontier for the Shock Society

Invited Speakers

• 9:00 AM – 9:20 AM: Jeff DellaVolpe MD MPH, Institute for Extracorporeal Life Support, Cardiogenic Shock Mechanisms
• 9:20 AM – 9:50 AM: Vedran Premuzic MD PhD, University Hospital Centre Zagreb, Blood purification in ECMO ($$)
• 9:50 AM – 10:10 AM: Perenlei Enkhbaatar MD PhD, University of Texas Medical Branch, Anticoagulation as an adverse event in an ECMO animal model
• 10:10 AM – 10:30 AM: Jason Bartos MD PhD, University of Minnesota, eCPR in ECMO ($$)

Moderators
Eric Schmidt MD, Massachusetts General Hospital

Hunter Moore MD, University of Colorado

Parallel Session 2 – Microvascular Dysfunction in Sepsis and Injury

Invited Speakers

• 9:00 AM – 9:20 AM
  Amily Guo MD PhD, University of Washington, Platelet interactions with CD8+ T cells in sepsis
• 9:20 AM – 9:40 AM: Eric Schmidt MD, Massachusetts General Hospital, Using a randomized controlled trial to study glycocalyx degradation during human sepsis

Oral Abstracts

• 9:40 AM – 9:50 AM: Adam Novak, SUNY Upstate Medical University, IMSC-DERIVED EXTRACELLULAR VESICLES ATTENUATE THE INFLAMMATORY RESPONSE IN SEPSIS (Abstract 4079477)
• 9:50 AM – 10:00 AM: Marissa Pokharel, Florida International University, INFLAMMATORY LUNG INJURY IS ASSOCIATED WITH ENDOTHELIAL CELL MITOCHONDRIAL FISSION (Abstract 4083967)
• 10:00 AM – 10:10 AM: Robert Richter, The University of Alabama at Birmingham, TRAUMA PROMOTES HEPARAN SULFATE MODIFICATIONS AND CLEAVAGE THAT DISRUPTS HOMEOSTATIC ENDOTHELIAL CELL GENE EXPRESSION (Abstract 4083969)
• 10:10 AM – 10:20 AM: Feng Wu, University of Maryland, FIBRINOGEN BASED RESUSCITATION MITIGATES LUNG HYPERPERMEABILTY AND ENDOTHELIOPATHY AND RESTORES IMMUNITY IN MICE WITH BACTERIAL PNEUMONIA AFTER HEMORRHAGIC SHOCK (Abstract 4076568)
• 10:20 AM – 10:30 AM: Desiree Pinto, MedStar Georgetown University Hospital, FIBRINOLYTIC ACTIVATION IS ASSOCIATED WITH MORTALITY AND EARLY ABNORMAL FIBRINOLYTIC PHENOTYPES AFTER BURN INJURY (Abstract 4083467)

Moderators
Philip Efron MD
Melanie Scott MD PhD

Plenary Session VII – An Update on NIH and DOD Research Priorities and Opportunities for Trauma, Sepsis, and Burns

Invited Speakers

• 10:45 AM – 11:05 AM: (PRERECORDED) Guofei Zhou, PhD - Program Director, NHLBI Division of Lung Diseases (DLD)
  NHLBI Research Priorities and Directions in Acute Lung Injury and ARDS
• 11:05 AM – 11:30 AM:  Xiaoli Zhao, PhD - Program Director, NIGMS
  NIGMS Research Opportunities and Updates  
• 11:30 AM – 11:55 PM:  Sandy Snyder, MSN, RN, CCRN-K – Program Manager Military Burn Research Program and Defense Medical Research Program-CDMRP
  DOD Research Priorities and Directions
• 11:55 PM – 12:15 PM: Q&A

Moderators
Tony Pusateri PhD, U.S. Army Institute of Surgical Research

Jeffery W. Shupp MD, Medstar Washington Hospital Center

Plenary Session VIII – Acute Burn Resuscitation

Invited Speakers

• 1:00 PM – 1:20 PM: John C. Kubasiak MD, Loyola University
  Current Clinical Practice on Acute Burn Resuscitation
• 1:20 PM – 1:40 PM: Anthony E. Pusateri PhD, U.S. Army Institute of Surgical Research, Acute Fibrinolytic and Endothelial Dysfunction after Burn Injury
• 1:40 PM – 2:00 PM: Myung S. Park MD MS, Mayo Clinic, Acute Burn-Induced Coagulopathy
• 2:00 PM – 2:20 PM: Lauren T. Moffatt PhD, Medstar Washington Hospital Center
  Acute Inflammatory Response to Burn Injury
• 2:20 PM – 2:40 PM: Jeffrey W. Shupp MD, Medstar Washington Hospital Center
  Plasma-inclusive Resuscitation of Burn Patients

Oral Abstracts

• 2:40 PM – 2:50 PM: Mary Grace Murray, Loyola University, PROBIOTIC AKKERMANSIA MUCINPHILA IN BURN INJURY AND ALCOHOL INTOXICATION (Abstract 4069298)
• 2:50 PM – 3:00 PM: Denise Hernandez, University of Florida, HUMAN MESENCHYMAL STEM CELL EXTRACELLULAR VESICLES REPROGRAM IMMUNE SIGNALING PATHWAYS IN BURN PATIENT IMMUNE CELLS (4082894)

Moderators
Joseph Jeevendra Martyn MD, Massachusetts General Research Institute
Marc Jeschke MD PhD, Health Sciences McMaster University

Parallel Session 5 – Myology and Catabolism in Skeletal Muscle

Invited Speakers

• 3:00 PM – 3:20 PM: Shingo Yasuhara MD PhD, Massachusetts General Research Institute, Defective quality control system of mitochondria in critical illnesses – a potential new therapeutic target
• 3:20 PM – 3:40 PM: Craig Porter PhD, University of Arkansas for Medical Sciences, Burn-induced muscle wasting: current understanding and future research opportunities
• 3:40 PM – 4:00 PM: Hiroshi Saito PhD, University of Kentucky, Inflammation, wasting/atrophy, and mitochondria dysfunction
• 4:00 PM – 4:20 PM: Joseph Jeevendra Martyn MD, Massachusetts General Research Institute, Motor neuron, microglia, and muscle crosstalk in muscle wasting of burns

Oral Abstracts

• 4:20 PM – 4:30 PM: Evan Barrios, University of Florida, SEX-SPECIFIC DIFFERENCES IN HUMAN MYELOID-DERIVED SUPPRESSOR CELL MITOCHONDRIAL METABOLISM AFTER SEPSIS (Abstract 4083804)

3:00 PM – 4:30 PM

Moderators
Jennifer Kaplan MD, Cincinnati Children’s Hospital
Marlene Starr PhD, University of Kentucky

Parallel Session 6 – Mechanisms of Organ Dysfunction Following Injury and Sepsis

Invited Speakers

• 3:00 PM – 3:20 PM: Mihir Atreya MD MPH, Cincinnati Children’s Hospital Medical Center, Scope of human induced pluripotent stem cells in critical illness research
• 3:20 PM – 3:40 PM: Mathias Majetschak MD PhD, University of South Florida, Cross-talk between stress and immunity: Roles of chemokine receptor – vasopressor receptor hetero-oligomers
• 3:40 PM – 4:00 PM: Andrew Lautz MD, Cincinnati Children’s Hospital Medical Center, Human induced pluripotent stem cells to understand cardiomyocyte dysfunction in sepsis

Oral Abstracts

• 4:00 PM – 4:10 PM: Satoshi Yamaga, The Feinstein Institutes for Medical Research, EXPOSURE TO RADIATION IMPAIRS MACROPHAGE BACTERIAL PHAGOCYTOSIS VIA ECIRP (Abstract 4073675)
• 4:10 PM – 4:20 PM: Marlene Starr, University of Kentucky, CIRCULATING LIPIDS MAY PROVIDE A SURVIVAL BENEFIT IN THE OBESE WITH SEPSIS (Abstract 4078393)
• 4:20 PM – 4:30 PM: Nina Mirabadi, University of Washington, DETECTION OF POST-TRAUMATIC INFECTION AND SEPSIS USING QUANTITATIVE MDSC MEASUREMENTS (Abstract 4083215)

4:40 PM – 6:00 PM

Moderators
Steven Schwulst MD, Northwestern Medicine
Letitia Bible MD, University of Florida 

Parallel Session 5 – Improving Neurologic Outcomes following Injury and Sepsis

Invited Speakers

• 4:40 PM – 5:00 PM: Kalev Freeman MD PhD, University of Vermont
  Echoes of Impact: Cardiovascular Sequelae of Traumatic Brain Injury
• 5:00 PM – 5:20 PM: Steven Schwulst MD, Northwestern Medicine, 

  The gut-brain axis as a novel therapeutic target in traumatic brain injury

Oral Abstracts

• 5:20 PM – 5:30 PM: Ravinder Nagpal, Florida State University, ENTERO-SEPTIC KLEBSIELLA PNEUMONIAE INFECTION AND PATHOBIOME INDUCE NEUROINFLAMMATORY AND COGNITIVE IMPAIRMENTS IN 3X TG MICE (Abstract 4083885)
• 5:30 PM – 5:40 PM: Alyson Galvan-Lara, University of Kentucky, EFFECTS OF APOLIPOPROTEIN E POLYMORPHISM ON POST-SEPSIS COGNITIVE DYSFUNCTION (Abstract 4083204)
• 5:40 PM – 5:50 PM: Mecca Islam, Northwestern University, SEX ASSOCIATED DIFFERENCES IN NEUROCOGNITIVE OUTCOMES AFTER TBI (Abstract 4083554)
• 5:50 PM – 6:00 PM: Andrew Hoisington, US Department of Veterans Affairs Mental Illness Research Education and Clinical Centers, GUT MICROBIOME AND INFLAMMATION AFTER EMERGENCY DEPARTMENT VISIT FOR MILD TRAUMATIC BRAIN INJURY (Abstract 4077363)

4:40 PM – 6:00 PM

Extremes of Age and their Importance in Injury and Sepsis Research

Moderators
Dan Hao PhD, Vanderbilt University
Shawn Larson MD, University of Florida

Parallel Session 6

• 4:40 PM – 4:50 PM: Ki Ho Park, University of Virginia, PRESERVING NEURONAL INTEGRITY AND MITIGATING INFLAMMATION TO COUNTER ISCHEMIC BRAIN INJURY IN AGING MICE (Abstract 4080581)
• 4:50 PM – 5:00 PM: Grace Fisler, Steven, and Alexandra Cohen Children's Medical Center: CHARACTERIZATION OF CIRCULATING INNATE IMMUNE PROFILE IN EARLY PEDIATRIC SEPSIS (Abstract 4078779)
• 5:00 PM – 5:10 PM: Jaimar Rincon, University of Florida, SINGLE-CELL TRANSCRIPTOME PROFILING REVEALS MYELOID-DERIVED SUPPRESSOR CELL (MDSC) HETEROGENEITY IN MURINE NEONATAL SEPSIS (Abstract 4083786)
• 5:10 PM – 5:20 PM: Dan Hao, Vanderbilt University, TRAINED IMMUNITY ENHANCES HOST RESISTANCE TO INFECTION IN AGING
• 5:20 PM – 5:30 PM: Hyebin Han, Northwestern University, FECAL MICROBIOTA TRANSPLANT WITH AGED GUT MICROBIOTA INCREASE SPECIES-NORMAL ANXIETY AS COMPARED TO YOUNG GUT MICROBIOTA (Abstract 4078779)